The entrepreneurial competencies of entrepreneurs with disabilities can be categorized and described according to many aspects.These typically cover personal competences and competences necessary for the operation of the business, which are the result of formal, non-formal and informal learning processes. Based on interviews with 29 entrepreneurs with disabilities, in our research we found that successful entrepreneurship requires integration experience in public education, the establishment of professional skills in institutional learning (e.g., higher education), but equally important are the skills acquired through non formal learning (e.g., sports, choir) and work experience, as well as ‘life experience’ that can be considered informal learning. Further important factors are the presence of a supportive educator, teacher or coach, as well as supported career guidance.